People with it have episodes of symptoms (sometimes called attacks). It makes blood vessels in your digits suddenly tighten (contract) more than they should. This can make the skin in your affected digits turn pale or lighter than your natural skin tone. Scleroderma is a rare condition that makes your body produce tissue that’s thicker than it should be. Scleroderma usually affects your skin, but can cause symptoms in any tissue throughout your body.
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- You should expect to manage scleroderma and its symptoms for the rest of your life.
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- If the result is abnormal, you will need a more specific blood test to look for scleroderma-specific autoantibodies.
- Most people with scleroderma don’t experience life-threatening complications.
- Scleroderma can cause so many different symptoms that it’s sometimes hard to notice at first.
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A collaborative approach to research is opening doors to new treatments and ultimately, a cure. Vitamin D is implicated in the pathophysiology of the disease. It may be a good idea to speak with your doctor if any of your symptoms are getting in the way of your daily life.
Potential complications of systemic sclerosis
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With SS, your tissue becomes thick and stiff, leading to swelling and pain. Cleveland Clinic takes a team approach to scleroderma treatment. We’ll help you slow its progression and manage your symptoms. Most people with scleroderma don’t experience life-threatening complications. Sjögren’s syndrome makes your body produce less moisture in certain glands — usually the salivary glands in your mouth and the glands in your eyes that produce tears. Some people with Sjögren’s syndrome experience muscle and joint pain, too.
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Scleroderma is a chronic condition, which means you’ll need to manage your symptoms for a long time (maybe the rest of your life). It can also cause life-threatening complications if it affects tissue in your organs. Call 911 (or your local emergency services number) or go to the emergency room if you feel like you’re having a heart attack, can’t breathe or can’t swallow. If you have scleroderma, your immune system triggers your body’s cells to produce too much collagen (a protein). Your body needs collagen to have strong, healthy connective tissue to support your organs and hold parts of your body in place. But when you produce too much of it, your skin and other tissue can be thicker and more fibrous than they should be.
Black people often have earlier onset and are more likely to have more skin involvement and lung disease. The first parts of the body to be affected are usually the fingers, hands, feet and face. In some people, the skin thickening also can involve the forearms, upper arms, chest, abdomen, lower legs and thighs. The color of affected skin can become lighter or darker, and skin may look shiny because of the tightness. The Scleroderma Clinic at Boston Medical Center is a multidisciplinary center that offers comprehensive care and cutting-edge research for patients with scleroderma.
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In some patients with diffuse forms of scleroderma a bone marrow transplant can also be considered. Scleroderma symptoms may range from minor to life-threatening. An early, common sign of scleroderma is color changes to the fingers called Raynaud’s phenomenon. Fingers or toes may look red, white, or blue, especially in cold temperatures and may be swollen, numb, painful or develop ulcers.
The condition worsens quickly in diffuse cutaneous systemic scleroderma, with organ damage occurring earlier than the other two types of SS. You then see fibrosis or scar tissue, also described as connective tissue growth, in response to a perceived injury or damage. Call 911 (or your local emergency number) or go to the emergency room if you’re experiencing heart attack symptoms like chest pain, trouble breathing or you feel like you can’t swallow. Scleroderma can cause so many different symptoms that it’s sometimes hard to notice at first. Visit a healthcare provider if you notice any new pain or other symptoms, especially if they’re getting worse. Even if something else is causing your symptoms, a provider will diagnose the cause and suggest treatments to manage them.
Living with Scleroderma
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Whether you’re planning a luxury sailing or searching for a great-value Mediterranean getaway, these cruises combine culture, sunshine, and adventure. At Hello Cruise, we bring together the best Barcelona to Greece cruise deals and itineraries from trusted UK travel agents – all in one place. In this case, you might find a cruise that starts in Barcelona but ends in Athens or another Greek port.
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. The disease can be either localized to the skin or involve other organs as well. Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure. Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin.
- It happens because of an exaggerated contraction of the small blood vessels in the fingers and toes in response to cold temperatures or emotional distress.
- Scleroderma results from an overactive immune system causing inflammation and tissues changes, especially fibrosis.
- Sometimes ILD can also lead to or exist with pulmonary hypertension.
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Keep in mind that many other conditions have similar symptoms to scleroderma. However, being informed and asking questions are the best ways to know for sure. There is loss of circulation that can lead to painful skin ulcers on fingers, toes, and other extremities. Loss of flexibility in the hands and severe skin tightening can impair the use of fingers and toes.